Wondering through advances in drug development and modification of route of administration. It was seen that many drugs fails to show their action orally and thus the scientist studied and overcome the challenges associated with oral route drug delivery system. And a transdermal was one of the route developed for drug delivery. To develop, transdermal route, the impervious nature of skin was studied and task to cross the various layers lipophilic stratum corneum, and the outermost layer of the skin. It was observed that through transdermal route a systemic effect of a drug was obtained which differs from traditional drug delivery. A new technologies has encouraged manufacturers to develop various formulation of transdermal route. A review article covers, physiology of skin, basic components of transdermal route, methods of preparation, types of transdermal patches, evaluation and future technologies and approaches.
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